IntroductionThe main challenge for cancer therapy lies in immuno-suppressive tumor micro-environment.Reprogramming tumor-associated macrophages (TAMs) into an anti-tumor phenotype is a promising strategy.MethodsA comprehensive analysis by combing multi-regional HOREHOUND single-cell, bulk and spatial transcriptome profiling with radiomics character
The Atlantic bluefin tuna, Thunnus thynnus, is a commercially important species that has been severely over-exploited in the recent past.Although the eastern Atlantic and Mediterranean stock is now showing signs of recovery, its current status remains very uncertain and as a consequence their recovery is dependent upon severe management informed by
Managing container loading and unloading operations at a container terminal using Intelligent Autonomous Vehicle (IAV) is challenging, especially at intersections in the yard, which are often inevitable.For ensuring efficient and accident-free management of these intersections, the IAV must cooperate by exchanging messages.Due to signal obstruction
Motorized transport is one of the main contributors to anthropogenic CO 2 emissions, which cause global warming.Other emissions, like nitrogen oxides or carbon monoxide, are detrimental to human health.A prominent way to understand and thus be able to minimize emissions is by using traffic simulations to evaluate different scenarios.In that way, on